P4.12 Electrochemical measurements of mouse intestinal serotonin and melatonin: Effects of age and daily melatonin supplementation

Aging is associated with subtle changes in gastrointestinal function and in the levels of intestinal hormones secreted. Enterochromaffin cells containing serotonin (5-HT) and melatonin may play an important role in maintaining gut function during aging. Our aim was to characterise the mucosal levels of 5-HT and melatonin in a mouse model of aging. (Source: Autonomic Neuroscience: Basic and Clinical)

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