Sleep and Rhythm Consequences of a Genetically Induced Loss of Serotonin

Conclusion: In this unique genetic paradigm, the melatonin deficiency (caused by a lack of its substrate, serotonin) may cause the ultradian sleep-wake rhythm.
Keywords: Sepiapterin reductase deficiency, hypersomnia, melatonin, ultradian sleep-wake rhythm, tetrahydrobiopterin, serotonin (Source: Sleep)

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