Impact of oral melatonin on the electroretinogram cone response

Conclusions:
Oral melatonin appears to reach the eye through the circulation. When it is administered at a time of day when it is not usually present, melatonin appears to reduce input to retinal cones. We believe that the impact of melatonin on retinal function should be taken into consideration when used without supervision in chronic self-medication for sleep or circadian disorder treatment. (Source: Journal of Circadian Rhythms)

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