Melatonin regulates delayed embryonic development in the short-nosed fruit bat, C. sphinx.

This study further showed a suppressive impact of melatonin on the progesterone receptor in the utero-embryonic unit; this effect might contribute to delayed embryonic development in C. sphinx. The results of the present study thus suggest that a high circulating melatonin level has a dual contribution in retarding embryonic development in C. sphinx by impairing progesterone synthesis as well as by inhibiting progesterone action by reducing expression of progesterone receptor in the utero-embryonic unit.
PMID: 19690096 [PubMed - as supplied by publisher] (Source: Reproduction)

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