Evidence that Refractoriness to Long and Short Daylengths Regulates Seasonal Reproductive Transitions in Mediterranean Goats
Two experiments were performed to assess the role of refractoriness to long and short daylengths in the timing of seasonal reproductive transitions in Mediterranean Malagueña goats. In the first experiment, intact adult does were either maintained under natural photoperiod conditions (NP; n = 5) or exposed to a constant long day photoperiod (LD [ndash] 16 h light/day; n = 5) from June to December 2005. In the second experiment, does were maintained either under NP conditions (n = 5) or received a series of subcutaneous melatonin implants (MI) from December 2005 to June 2006 to mimic a short day signal (n = 5). In both experiments, ovulatory activity was assayed by determining progesterone concentrations in blood samples collected twice per week. The onset of seasonal ovulatory activity di…
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Melatonin precursor stimulates growth factor circuits in brain
N-acetylserotonin, the immediate precursor to melatonin, activates the same growth circuits in the brain as BDNF (brain-derived neurotrophic factor). The results have implications for how some antidepressants function and suggest that the molecules and pathways involved in mood regulation and circadian rhythms are intertwined. (Source: ScienceDaily Headlines)
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Melatonin Precursor Stimulates Growth Factor Circuits In Brain
Scientists at Emory University School of Medicine have discovered unexpected properties for a precursor to melatonin, the hormone that regulates sleep cycles. Melatonin is produced from the neurotransmitter serotonin in a daily rhythm that peaks at night. Melatonin’s immediate precursor, N-acetylserotonin, was not previously thought to have effects separate from those of melatonin or serotonin… (Source: Biology / Biochemistry News From Medical News Today)
Melatonin precursor stimulates growth factor circuits in brain
(Emory University) N-acetylserotonin, the immediate precursor to melatonin, activates the same growth circuits in the brain as BDNF (brain-derived neurotrophic factor). The results have implications for how some antidepressants function and suggest that the molecules and pathways involved in mood regulation and circadian rhythms are intertwined. (Source: EurekAlert! - Social and Behavioral Science)
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